Preview

Minimally Invasive Cardiovascular Surgery

Advanced search

Minimally invasive aortocoronary bypass grafting via left minithoracotomy: technique, results and evolution of the method

Abstract

Aim: total arterial coronary bypass performed via minimally invasive access through an anterolateral mini-thoracotomy has significant advantages due to complete myocardial arterial revascularization. At the same time, it should be noted that this technique is technically challenging and requires overcoming a significant learning curve. This study presents a comprehensive analysis of the dynamics of development and improvement of the development and refinement of a surgical program over an 8-year period.

Materials and methods: a prospective data collection was performed for all patients who underwent this procedure at our institution between January 2015 and December 2023. During this period, the program underwent several modifications, including: optimization of surgical access using various available instruments and operative time management; standardization of the technique for all off-pump coronary artery bypass procedures; and implementation of a mentoring system for the surgical team. Changes in the quality control system involved a transition from routine postoperative coronary angiography to imaging only when clinically indicated.The effectiveness of these measures was evaluated according to the following parameters: Primary endpoint: in-hospital mortality. Secondary endpoints: procedure duration and incidence of perioperative myocardial infarction. The analysis was performed by comparing two time periods: Group 1 (n=137): patients operated on during the first 4 years of the study; Group 2 (n=142): patients operated on during the second 4 years.

Results: a total of 279 consecutive patients underwent elective total arterial minimally invasive coronary artery bypass grafting at our institution during the study period. The mean age was 66 years (±7), 86% (n=241) were male, and 33.1% (n=77) had diabetes mellitus. Three-vessel desease was present in 53% of patients (n=123), and left main coronary artery desease in 43% (n=101).The overall 30-day mortality was 0.4% (n=1). Compared to the initial 4-year period, the latter patient group showed threefold reduction in the incidence of perioperative myocardial infarction (4.3% vs. 1.4%, p=0.1) and a statistically significant reduction in the time of surgery (275±59.5 minutes vs. 246±72.6 minutes, p < 0.001).

Conclusion: total arterial minimally invasive coronary artery bypass grafting is a feasible surgical approach that can yield excellent results even during the initial learning phase. An evolving educational program can facilitate a smooth transition from off-pump coronary artery bypass grafting to minimally invasive coronary artery bypass grafting in selected patients at highly specialized cardiac surgery centers.

About the Authors

Aleksandr S. Verevkin
Leningrad Regional Clinical Hospital
Россия

Aleksandr S. Verevkin ­ - M.D., Ph.D., Cardiovascular Surgeon, Cardiosurgical Department

5­2 Lunacharskogo St., St. Petersburg, 194291



Vadim A. Popov
FSBU «National Medical Research Center of Surgery named after A.V. Vishnevsky» Ministry of Health of Russia
Россия

Vadim A. Popov - M.D., Ph.D., Professor, Head of the Department of Cardiac Surgery

27, Bolshaya Serpukhovskaya Street, Moscow, 117997



Michael Borger
University Hospital Leipzig
Германия

Michael Borger ­-  M.D., Ph.D., Professor, Cardiovascular Surgeon, director

39, Strumpelstrasse, Leipzig, Germany, 04289



References

1. Neumann F.J., Sousa-Uva M., Ahlsson A. et al. 2018 ESC/EACTS Guidelines on myocardial revascularization. EuroIntervention J Eur Collab Work Group Interv Cardiol Eur Soc Cardiol. 2019;14(14):1435–534. DOI: 10.4244/EIJY19M01_01

2. Harskamp R.E., Bonatti J.O., Zhao D.X. et al. Standardizing definitions for hybrid coronary revascularization. J Thorac Cardiovasc Surg. 2014;147(2):556–60. DOI: 10.1016/j.jtcvs.2013.10.019

3. Loop F.D., Lytle B.W., Cosgrove D.M. et al. Influence of the internal-mammary-artery graft on 10-year survival and other cardiac events. N Engl J Med. 1986;314(1):1–6. DOI: 10.1056/NEJM198601023140101

4. Taggart D.P., Benedetto U., Gerry S. et al. Bilateral versus Single Internal-Thoracic-Artery Grafts at 10 Years. N Engl J Med. 2019;380(5):437 46. DOI : 10.1056/NEJM198601023140101

5. Head SJ, Milojevic M, Taggart DP, Puskas JD. Current Practice of State-of-the-Art Surgical Coronary Revascularization. Circulation. 2017 Oct 3;136(14):1331–45. DOI: 10.1161/CIRCULATIONAHA.116.022572

6. Gaudino M., Audisio K., Rahouma M. et al. Association between sternal wound complications and 10-year mortality following coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2023;166(2):532-539.e4. DOI: 10.1016/j.jtcvs.2021.10.067

7. Davierwala P.M., Verevkin A., Sgouropoulou S. et al. Minimally invasive coronary bypass surgery with bilateral internal thoracic arteries: Early outcomes and angiographic patency. J Thorac Cardiovasc Surg. 2021;162(4):1109-1119.e4. DOI: 10.1016/j.jtcvs.2019.12.136

8. Webster A.C., Nagler E.V., Morton R.L. Chronic Kidney Disease. The Lancet. 2017;389(10075):1238–52. DOI : 10.1016/S0140-6736(16)32064-5

9. Thygesen K., Alpert J.S., Jaffe A.S. et al Third Universal Definition of Myocardial Infarction. J Am Coll Cardiol. 2012;60(16): 1581–98. DOI: 10.1016/j.jacc.2012.08.001

10. Truszkiewicz K., Poręba R., Gać P. Radiological Cardiothoracic Ratio in Evidence-Based Medicine. J Clin Med. 2021;10(9):2016. DOI: 10.3390/jcm10092016

11. McGinn J.T., Usman S., Lapierre H. Minimally invasive coronary artery bypass grafting: dual-center experience in 450 consecutive patients. Circulation. 2009;120(11 Suppl): S78-84. DOI: 10.1161/CIRCULATIONAHA.108.840041

12. Babliak O., Demianenko V., Melnyk Y. Complete Coronary Revascularization via Left Anterior Thoracotomy. Innov Phila Pa. 2019;14(4):330–41. DOI: 10.1177/1556984519849126

13. Kikuchi K., Chen X., Mori M. Perioperative outcomes of off-pump minimally invasive coronary artery bypass grafting with bilateral internal thoracic arteries under direct vision†. Interact Cardiovasc Thorac Surg. 2017;24(5):696–701. DOI: 10.1093/icvts/ivw431

14. Mowatt G., Cummins E., Waugh N. et al. Systematic review of the clinical effectiveness and cost-effectiveness of 64-slice or higher computed tomography angiography as an alternative to invasive coronary angiography in the investigation of coronary artery disease. Health Technol Assess Winch Engl. 2008;12(17):iii–iv, ix 143. DOI: 10.3310/hta12170

15. Berman D.S., Hachamovitch R., Shaw L.J. et al. Roles of nuclear cardiology, cardiac computed tomography, and cardiac magnetic resonance: 26 439 assessment of patients with suspected coronary artery disease. J Nucl Med Off Publ Soc Nucl Med. 2006;47(1):74–82. PMID: 16391190

16. Cademartiri F., Casolo G., Clemente A. et al. Coronary CT angiography: a guide to examination, interpretation, and clinical indications. Expert Rev Cardiovasc Ther. 2021;19(5):413–25. DOI: 10.1080/14779072.2021.1915132

17. Liu J.J., Kong Q.Y., You B. et al. Surgical Challenges in Multi Vessel Minimally Invasive Coronary Artery Bypass Grafting. J Intervent Cardiol. 2021; 2021:1195613. DOI: 10.1155/2021/1195613

18. Puskas J.D., Williams W.H., Mahoney E.M. et al. Off-pump vs conventional coronary artery bypass grafting: early and 1-year graft patency, cost, and quality-of-life outcomes: a randomized trial. JAMA. 2004;291(15):1841–9. DOI:10.1001/jama.291.15.1841

19. Navia D., Vrancic M., Vaccarino G. et al. Total arterial off pump coronary revascularization using bilateral internal thoracic arteries in triple-vessel disease: surgical technique and clinical outcomes. Ann Thorac Surg. 2008;86(2):52430. DOI : 10.1016/j.athoracsur.2008.04.069

20. Nambiar P., Kumar S., Mittal C.M. Minimally invasive coronary artery bypass grafting with bilateral internal thoracic arteries: Will this be the future? J Thorac Cardiovasc Surg. 2018;155(1):190–7. DOI: 10.1016/j.jtcvs.2017.07.088

21. Davierwala P.M., Leontyev S., Garbade J. et al. Off-pump coronary artery bypass surgery with bilateral internal thoracic arteries: the Leipzig experience. Ann Cardiothorac Surg. 2018;7(4):483–91. DOI: 10.21037/acs.2018.06.15

22. Houlind K., Kjeldsen B.J., Madsen S.N. et al. On-pump versus off-pump coronary artery bypass surgery in elderly patients: results from the Danish on-pump versus off-pump randomization study. Circulation. 2012;125(20):2431–9. DOI:10.1161/CIRCULATIONAHA.111.052571

23. Chan V., Lapierre H., Sohmer B. et al. Handsewn proximal anastomoses onto the ascending aorta through a small left thoracotomy during minimally invasive multivessel coronary artery bypass grafting: a stepwise approach to safety and reproducibility. Semin Thorac Cardiovasc Surg. 2012;24(1):79–83. DOI: 10.1053/j.semtcvs.2011.12.010

24. Rodriguez M.L., Lapierre H.R., Sohmer B. et al. Mid-Term Follow-up of Minimally Invasive Multivessel Coronary Artery Bypass Grafting: Is the Early Learning Phase Detrimental? Innov Phila Pa. 2017;12(2):116–20. DOI: 10.1097/IMI.0000000000000353

25. Kayatta M.O., Halkos M.E., Narayan P. Minimally invasive coronary artery bypass grafting. Indian J Thorac Cardiovasc Surg. 2018;34(Suppl 3):302–9. DOI: 10.1007/s12055-017-0631-x


Review

For citations:


Verevkin A.S., Popov V.A., Borger M. Minimally invasive aortocoronary bypass grafting via left minithoracotomy: technique, results and evolution of the method. Minimally Invasive Cardiovascular Surgery. 2025;1(3):52-61. (In Russ.)

Views: 83

JATS XML


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.