The immediate results of coronary bypass surgery "on a working heart" in patients with coronary artery disease in the incubation period of a new coronavirus infection (COVID-19)
Abstract
The aim of the research: to analyze the results of coronary bypass surgery without IC on a "working heart" in patients with coronary artery disease performed during the incubation period of COVID-19.
Materials and methods: From January to December 2020, 305 patients with coronary artery disease were operated in the cardiac surgery Department No. 1 of the GBUZ IOCB. All patients were operated with access from a median sternotomy on a "working heart" within 1-5 days after hospitalization. 72 hours before hospitalization, all patients were tested for SARS-CoV-2 coronavirus RNA and had a negative result. Of the 305 operated patients, 8 (2.6%) underwent COVID-19 during hospitalization, confirmed by PCR for SARSCoV-2. In the biochemical analysis of blood, elevated levels of C-reactive protein and ferritin were noted. According to CT data, all patients had lung lesions.
Results: Depending on the condition, patients were transferred to the PITiR or general wards for the treatment of COVID-19 patients. Conservative treatment was carried out in accordance with the recommendations of the Ministry of Health of Russia. The time of stay of patients in the hospital was 37.6 (28-45) days. After treatment, 5 patients were discharged in satisfactory condition, 3 died. Hospital mortality was 37.5%.
Conclusion: Thus, a small number of observations of CHD patients operated on during the incubation period of COVID-19 with the exception of IC on a "working heart" allows us to draw a preliminary conclusion that postoperative mortality depends on the severity of lung damage caused by a new coronavirus infection (COVID-19) with the clinic of acute respiratory syndrome (SARS-CoV-2).
About the Authors
V. A. PodkamenniyRussian Federation
Vladimir A. Podkamenny – cardiovascular surgeon Cardiosurgical dep. №1, MD, professor
664079, Irkutsk, mkr. Yubileyniy 100
phone 0073952407851
A. A. Sharavin
Russian Federation
Anatoly A. Sharavin - cardiovascular surgeon Cardiosurgical dep. №1
664079, Irkutsk, mkr. Yubileyniy 100
phone 0073952407851
Y. V. Zheltovsky
Russian Federation
Yury V. Zheltovsky - cardiovascular surgeon Cardiosurgical dep. №1, MD, professor
664079, Irkutsk, mkr. Yubileyniy 100,
phone 0073952407851
B. S. Denisyuk
Russian Federation
Bogdan S. Denisyuk - resident of the Department of Cardiovascular Surgery
664049, Irkutsk, Yubileyniy 100
References
1. Aghagoli G., Gallo Marin B., Soliman L.B., Sellke F.W. Cardiac involvement in COVID-19 patients: risk factors, predictors, and complications: a review. J Card Surg.2020.35(6).1302-1305
2. Nishiga M., Wang D.W., Han Y., Lewis D.B., Wu J.C. COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives. Nat Rev Cardiol. 2020. №17(9). 543-558.
3. Libby P., Lüscher T. COVID-19 is, in the end, an endothelial disease. Eur Heart J. 2020. №41(32). 3038-3044
4. Guzik T.J., Mohiddin S.A., Dimarco A., et al. COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovasc Res. 2020. №116(10). 1666-1687
5. Zhou F., Yu T., Du R. et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020. 395(10229). 1054–62
6. Lei S., Jiang F., Su W., et al. Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection. EClinicalMedicine. 2020; .21.100331
7. Bikdeli B., Madhavan M.V., Jimenez D., Chuich T., Dreyfus I., Driggin E., Nigoghossian C., Ageno W., Madjid M., Guo Y., Tang LV., Hu Y., Giri J., Cushman M., Quere I., Dimakakos EP., Gibson CM., Lippi G., Favaloro EJ., Fareed J., Caprini JA., Tafur AJ., Burton JR., Francese DP., Wang EY., Falanga A., McLintock C., Hunt BJ., Spyropoulos AC., Barnes GD., Eikelboom JW., Weinberg L., Schulman S., Carrier M., Piazza G., Beckman JA., Steg PG., Stone GW., Rosenkranz S., Goldhaber SZ., Parikh SA., Monreal M., Krumholz HM., Konstantinides SV., Weitz JI., Lip GYH: Global COVID-19 Thrombosis Collaborative Group, Endorsed by the ISTH, NATF, ESVM, and the IUA, Supported by the ESC Working Group on Pulmonary Circulation and Right Ventricular Function. COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy and followup: JACC state of the art review. J Am Coll Cardiol. 2020.75.2950-2973
8. Yandrapall S., Cooper H., Malekan R. Successful coronary artery bypass operation in a SARSCoV-2 infected patient with acute coronary syndrome. J Card Surg. 2020.35(9).2361-3.
9. Rescigno G., Firstenberg M., Rudez I., et al. A case of postoperative covid-19 infection after cardiac surgery: Lessons learned. Heart Surg Forum. 2020.23(2).231-233
10. Kuznetsov D.V., Gevorgyan A.A., Novokshenov V.V., Kryukov A.V., Polyaeva M.V., Lyas M.N., Khalmetova A.A., Duplyakov D.V. Coronary artery bypass grafting in patients with coronary artery disease and COVID-19: search for an optimal strategy. Russian Journal of Cardiology. 2021.26(1S).4342. (In Russ.)
Review
For citations:
Podkamenniy V.A., Sharavin A.A., Zheltovsky Y.V., Denisyuk B.S. The immediate results of coronary bypass surgery "on a working heart" in patients with coronary artery disease in the incubation period of a new coronavirus infection (COVID-19). Minimally Invasive Cardiovascular Surgery. 2024;3(3):60-65. (In Russ.)