Сonventional and hybrid aortic arch repair for aortic dissection
Abstract
Aim: To conduct comparative analysis of the early and long-term results of surgical reconstruction of the aortic arch with and without the “Frozen elephant trunk” technique in patients with aortic dissection.
Methods: A retrospective study has been conducted, 72 patients with acute and chronic aortic dissection who underwent surgical treatment were enrolled. All patients were divided into two groups. Group I (non- FET, n=17) consisted of patients who underwent conventional reconstructive surgery without using the “Frozen elephant trunk” technique. Group II (FET, n=55) included patients who underwent the “Frozen elephant trunk” procedure. A comparative analysis of early and mid-term postoperative results was carried out.
Results: In the early postoperative period in the non-FET and FET groups, the incidence of transient neurological complications was 0 vs. 3.6% (p>0.999) and cerebral stroke was 0 vs. 3.6% (p>0.999). Paraplegia was not noted in any of the groups. The need for prolonged respiratory support after surgery was recorded in 82.4% of cases in patients in the non-FET group and in 17.6% in the FET group (p<0.001). Acute kidney injury was diagnosed in 17.6% and 5.9% in the non-FET and FET groups, respectively (p=0.601). Early postoperative mortality in the non-FET group was 17.6%, in the FET group – 7.3% (p=0.344). Patient survival for 5 years after surgery was 71% in the non-FET group and 76% in the FET group. Freedom from distal aortic reintervention was 86% in the non-FET group and 100% in the FET group (p=0.861). Freedom from negative remodeling of the thoracoabdominal aorta in the non-FET and FET groups reached comparable values, not exceeding 62 and 62%, respectively (p=0.875).
Conclusion. The “Frozen elephant trunk” technique in the treatment of patients with aortic dissection is promising and characterized by satisfactory early and long-term results in this category of patients.
Keywords
About the Authors
B. N. KozlovRussian Federation
Kozlov Boris N., M.D., Ph.D., Head of the Department of Cardiovascular Surgery
Kyiv St. 111A, Tomsk, Tomsk Region, 634012
D. S. Panfilov
Russian Federation
Panfilov Dmitry S., M.D., Ph.D., senior researcher at the Department of Cardiovascular Surgery
Kyiv St. 111A, Tomsk, Tomsk Region, 634012
V. L. Lukinov
Russian Federation
Lukinov Vitaly L., Ph.D., Head of the Laboratory of Numerical Analysis of Stochastic Differential Equations
Academician Lavrentyev Ave. 6, Novosibirsk, 630090
N. O. Panfilova
Russian Federation
Panfilova Natalia O., M.D., Ph.D., Head of the Radiology Department,
Maurice Thorez St. 22Zh, Novokuznetsk, Kemerovo Region, 654038
E. V. Lelik
Russian Federation
Lelik Evgeniya V., M.D., Ph.D., cardiologist at the Cardiac Surgery Department No. 1,
Kyiv St. 111A, Tomsk, Tomsk Region, 634012
References
1. Khullar V, Schaff HV, Dearani JA, Daly RC, Greason KL, Joyce LD, Pochettino A. Open surgical repair remains the gold standard for treating aortic arch pathology. Ann Thorac Surg. 2017; 103:1413–1420. http://dx.doi.org/10.1016/j.athoracsur.2016.08.064
2. Belov U.V., Charchan E.R., Stepanenko A.B., Gens A.P., Hachatryan Z.R. Opyt hirurgicheskogo lecheniya bol'nyh s rassloeniem aorty 1-go tipa po DeBakey. Hirurgiya. 2018; 7: 8-17. (In Russ)] https://doi.org/10.17116/hirurgia201878
3. Di Eusanio M, Borger M, Petridis FD, Leontyev S, Pantaleo A, Moz M, Mohr F, Di Bartolomeo R. Conventional versus frozen elephant trunk surgery for extensive disease of the thoracic aorta. J Cardiovasc Med. 2014, 15:803–809. doi:10.2459/JCM.0b013e328364559c; Shrestha M, Martens A, Krüger H, Maeding I, Ius F, Fleissner F, Haverich A. Total aortic arch replacement with the elephant trunk technique: single-centre 30-year results. Eur J Cardiothorac Surg. 2014;45:289–296. doi:10.1093/ejcts/ezt359
4. Leontyev S, Misfeld M, Daviewala P, Borger MA, Etz CD, Belaev S, Seeburger J, Holzhey D, Bakhtiary F, Mohr FW. Early- and medium-term results after aortic arch replacement with frozen elephant trunk techniques—a single center study. Ann Cardiothorac Surg. 2013;2(5):606-611. doi: 10.3978/j.issn.2225-319X.2013.09.22
5. Verhoye J-P, Soulami RB, Fouquet O, Ruggieri VG, Kaladji A, Tomasi J, Sellin M, Farhat F, Anselmi A.. Elective frozen elephant trunk procedure using the E-Vita Open. Plus prosthesis in 94 patients: a multicentre French registry. Eur J Cardiothorac Surg. 2017;52(4):733–739. doi:10.1093/ejcts/ezx159
6. Jakob H, Dohle D, Benedik J, Janosi RA, Schlosser T, Wendt D, Thielmann M, Erbel R, Tsagakis K. Long- term experience with the E-vita Open hybrid graft in complex thoracic aortic disease. Eur J Cardiothorac Surg. 2017; 51(2):329–338, https://doi.org/10.1093/ejcts/ezw340
7. Shrestha M, Martens A, Kaufeld T, Beckmann E, Bertele S, Krueger H, Neuser J, Fleissner F, Ius F, Alhadi FA, Hanke J, Schmitto JD, Cebotari S, Karck M, Haverich A, Chavan A. Single-centre experience with the frozen elephant trunk technique in 251 patients over 15 years. Eur J Cardiothorac Surg. 2017; doi:10.1093/ejcts/ezx218
8. Kato M, Ohnishi K, Kaneko M, Ueda T, Kishi D, Mizushima T, Matsuda H. New graft-implanting method for thoracic aortic aneurysm or dissection with a stented graft. Circulation. 1996; 94 (9): 188-193
9. Charchyan E.R., Abugov S.A., Hachatryan Z.R., Pureckij M.V., Hovrin V.V., Skvorcov A.A., Belov YU.V. Osobennosti techeniya posleoperacionnogo perioda u pacientov s rassloeniem aorty I tipa po DeBakey: kriterii ocenki remodelirovaniya aorty i faktorov riska progressirovaniya zabolevaniya. Hirurgiya. ZHurnal im. N.I. Pirogova (In Russ). 2019;(5):6-17. Doi 10.17116/hirurgia20190516;
10. Inoue Y, Matsuda H, Omura A, Seike Y, Uehara K, Sasaki H, Kobayashi J. Long-term outcomes of total arch replacement with the non-frozen elephant trunk technique for Stanford Type A acute aortic dissection. Interact CardioVasc Thorac Surg. 2018;27:455–460. doi:10.1093/icvts/ivy094; Jakob H, Dohle D, Benedik J, Janosi RA, Schlosser T, Wendt D, Thielmann M, Erbel R, Tsagakis K. Long-term experience with the E-vita Open hybrid graft in complex thoracic aortic disease. Eur J Cardiothorac Surg. 2017; 51(2):329–338, https://doi.org/10.1093/ejcts/ezw340
11. Shrestha M, Martens A, Kaufeld T, Beckmann E, Bertele S, Krueger H, Neuser J, Fleissner F, Ius F, Alhadi FA, Hanke J, Schmitto JD, Cebotari S, Karck M, Haverich A, Chavan A. Single-centre experience with the frozen elephant trunk technique in 251 patients over 15 years. Eur J Cardiothorac Surg. 2017 doi:10.1093/ejcts/ezx218
12. Mkalaluh S, Szczechowicz M, Mashhour A, Zhigalov K, Easo J, Eichstaedt HC, Ennker J, Thomas RP, Chavan A, Weymann A. Total aortic arch replacement using elephant trunk or frozen elephant trunk technique: a case-control matching study. J Thorac Dis. 2018;10(11):6192-6200. doi: 10.21037/jtd.2018.10.42
13. Leontyev S, Misfeld M, Daviewala P, Borger MA, Etz CD, Belaev S, Seeburger J, Holzhey D, Bakhtiary F, Mohr FW. Early- and medium-term results after aortic arch replacement with frozen elephant trunk techniques—a single center study. Ann Cardiothorac Surg. 2013;2(5):606-611. doi: 10.3978/j.issn.2225-319X.2013.09.22
14. Charchyan E.R., Abugov S.A., Hachatryan Z.R., Pureckij M.V., Hovrin V.V., Skvorcov A.A., Belov YU.V. Osobennosti techeniya posleoperacionnogo perioda u pacientov s rassloeniem aorty I tipa po DeBakey: kriterii ocenki remodelirovaniya aorty i faktorov riska progressirovaniya zabolevaniya. Hirurgiya. ZHurnal im. N.I. Pirogova (In Russ). 2019;(5):6-17. Doi 10.17116/hirurgia20190516
15. Leontyev S, Misfeld M, Daviewala P, Borger MA, Etz CD, Belaev S, Seeburger J, Holzhey D, Bakhtiary F, Mohr FW. Early- and medium-term results after aortic arch replacement with frozen elephant trunk techniques—a single center study. Ann Cardiothorac Surg. 2013;2(5):606-611. doi: 10.3978/j.issn.2225-319X.2013.09.22
16. Mkalaluh S, Szczechowicz M, Mashhour A, Zhigalov K, Easo J, Eichstaedt HC, Ennker J, Thomas RP, Chavan A, Weymann A. Total aortic arch replacement using elephant trunk or frozen elephant trunk technique: a case-control matching study. J Thorac Dis. 2018;10(11):6192-6200. doi: 10.21037/jtd.2018.10.42
17. Shrestha M, Bachet J, Bavaria J, Carrel TP, De Paulis R, Di Bartolomeo R, Etz CD, Grabenwöger M, Grimm M, Haverich A, Jakob H, Martens A, Mestres CA, Pacini D, Resch T, Schepens M, Urbanski PP, Czerny M.. Current status and recommendations for use of the frozen elephant trunk technique: a position paper by the Vascular Domain of EACTS. Eur J Cardiothorac Surg. 2015;47:759–769. doi:10.1093/ejcts/ezv085
18. Flores J, Kunihara T, Shiiya N, Yoshimoto K, Matsuzaki K, Yasuda K. Extensive deployment of the stented elephant trunk is associated with an increased risk of spinal cord injury. The Journal of Thoracic and Cardiovascular Surgery. 2006;131(2):336-342. doi:10.1016/j.jtcvs.2005.09.050
19. Tian DH, Wan B, Di Eusanio M, Black D, Yan TD. A systematic review and meta-analysis on the safety and efficacy of the frozen elephant trunk technique in aortic arch surgery. Ann Cardiothorac Surg 2013;2(5):581-591. doi: 10.3978/j.issn.2225-319X.2013.09.07
20. Leontyev S, Misfeld M, Daviewala P, Borger MA, Etz CD, Belaev S, Seeburger J, Holzhey D, Bakhtiary F, Mohr FW. Early- and medium-term results after aortic arch replacement with frozen elephant trunk techniques—a single center study. Ann Cardiothorac Surg. 2013;2(5):606-611. doi: 10.3978/j.issn.2225-319X.2013.09.22
21. Ranucci M, Bozzetti G, Ditta A, Cotza M, Carboni G, Ballotta A. Surgical reexploration after cardiac operations: why a worse outcome? Ann Thorac Surg. 2008; 86: 1557–1562. doi:10.1016/j.athoracsur.2008.07.114;
22. Knapik P, Knapik M, Zembala MO, Przybyłowski P, Nadziakiewicz P, Hrapkowicz T, Ciesla D, Deja M, Suwalski P, Jasinski M, Tobota Z, Maruszewski BJ, Zembala M. In-hospital and mid-term outcomes in patients reoperated on due to bleeding following coronary artery surgery (from the KROK Registry). Interact CardioVasc Thorac Surg. 2019;29:237–43. doi:10.1093/icvts/ivz089
23. Brat R, Gaj J, Barta J. Early and mid-term outcomes of the aortic arch surgery: experience from the low-volume centre. Journal of Cardiothoracic Surgery. 2015; 10: 31. Doi 10.1186/s13019-015-0229-6; Lin H-H, Liao S-F, Wu C-F, Li P-C, Li M-L.
24. Outcome of frozen elephant trunk technique for acute type A aortic dissection as systematic review and meta-analysis. Medicine. 2015;94(16):e694. doi: 10.1097/MD.0000000000000694
25. Panfilov D.S., Kozlov B.N., Zatolokin V.V., Ponomarenko I.V., Hodashinskij I.A., SHipulin V.M. Profilaktika gemorragicheskih oslozhnenij pri operaciyah na grudnoj aorte. Rossijskij kardiologicheskij zhurnal (In Russ). 2018;(11):70-76. https://doi.org/10.15829/1560-4071-2018-11-70-76
26. Amano K, Takami Y, Ishikawa H, Ishida M, Tochii M, Akita K, Sakurai Y, Noda M, Takagi Y. Lower body ischaemic time is a risk factor for acute kidney injury after surgery for type A acute aortic dissection. Interact CardioVasc Thorac Surg. 2019; doi:10.1093/icvts/ivz220
27. Fang Z, Wang G, Liu Q, Zhou H, Zhou S, Lei G, Zhang C, Yang L, Shi S, Li J, Qian X, Sun X, Wei B, Yu C. Moderate and deep hypothermic circulatory arrest has a comparable effect on acute kidney injury after total arch replacement with frozen elephant trunk procedure in type A aortic dissection. Interact CardioVasc Thorac Surg. 2019;29:130-136. doi:10.1093/icvts/ivz092
28. Mkalaluh S, Szczechowicz M, Mashhour A, Zhigalov K, Easo J, Eichstaedt HC, Ennker J, Thomas RP, Chavan A, Weymann A. Total aortic arch replacement using elephant trunk or frozen elephant trunk technique: a case-control matching study. J Thorac Dis. 2018;10(11):6192-6200. doi: 10.21037/jtd.2018.10.42
29. Tochii M, Takami Y, Ishikawa H, Ishida M, Higuchi Y, Sakurai Y, Amano K, Takagi Y. Aortic remodeling with frozen elephant trunk technique for Stanford type A aortic dissection using Japanese J-graft open stent graft. Heart Vessels. 2019;34(2):316-317. doi:10.1007/s00380-018-1268-4
30. Leontyev S, Misfeld M, Daviewala P, Borger MA, Etz CD, Belaev S, Seeburger J, Holzhey D, Bakhtiary F, Mohr FW. Early- and medium-term results after aortic arch replacement with frozen elephant trunk techniques—a single center study. Ann Cardiothorac Surg. 2013;2(5):606-611. doi: 10.3978/j.issn.2225-319X.2013.09.22
31. Mkalaluh S, Szczechowicz M, Mashhour A, Zhigalov K, Easo J, Eichstaedt HC, Ennker J, Thomas RP, Chavan A, Weymann A. Total aortic arch replacement using elephant trunk or frozen elephant trunk technique: a case-control matching study. J Thorac Dis. 2018;10(11):6192-6200. doi: 10.21037/jtd.2018.10.42
32. Shrestha M, Beckmann E, Krueger H, Fleissner F, Kaufeld T, Koigeldiyev N, Umminger J, Ius F, Haverich A, Martens A. The elephant trunk is freezing: The Hannover experience. J Thorac Cardiovasc Surg. 2015;149:1286-1293. http://dx.doi.org/10.1016/j.jtcvs.2015.01.044
33. Hanif H, Dubois L, Ouzounian M, Peterson MD, El-Hamamsy I, Dagenais F, Hassan A, Chu MWA. Aortic arch reconstructive surgery with conventional techniques versus frozen elephant trunk: a systematic review and meta-analysis. Can J Cardiol. 2018;34(3):262-273. doi: 10.1016/j.cjca.2017.12.020
34. Shrestha M, Beckmann E, Krueger H, Fleissner F, Kaufeld T, Koigeldiyev N, Umminger J, Ius F, Haverich A, Martens A. The elephant trunk is freezing: The Hannover experience. J Thorac Cardiovasc Surg. 2015;149:1286-1293. http://dx.doi.org/10.1016/j.jtcvs.2015.01.044
35. Leontyev S, Borger MA, Etz CD, Moz M, Seeburger J, Bakhtiary F, Misfeld M, Mohr FW. Experience with the conventional and frozen elephant trunk techniques: a single-centre study. Eur J Cardiothorac Surg. 2013;44:1076–1083. doi:10.1093/ejcts/ezt252
Review
For citations:
Kozlov B.N., Panfilov D.S., Lukinov V.L., Panfilova N.O., Lelik E.V. Сonventional and hybrid aortic arch repair for aortic dissection. Minimally Invasive Cardiovascular Surgery. 2024;3(4):16-35. (In Russ.)